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Vitamin B12 deficiency thus leads to the poor regeneration of and gradual damage to the myelin sheaths (29)

This requires careful medical guidance and individual assessment to ensure safety for both mother and baby

If a patient is obese, drugs that do not readily penetrate fat (eg, gentamicin, digoxin, tacrolimus, gemcitabine) should have their volumes calculated from fat-free mass (FFM) as shown below